“We are delighted to be working in partnership with SOLVE FSHD and greatly appreciate the invaluable support for the development of MDL-103,” said Haru Morita, CEO of Modalis. “This strategic collaboration is a strong validation of Modalis’s CRISPR-GNDM^® technology and our MDL-103 program. As a pioneer in this technology, we have demonstrated promising long-term drug efficacy in mouse models, shown durable target engagement and safety in non-human primates, and exhibited excellent biodistribution in neuromuscular disorders. We believe that MDL-103, which incorporates CRISPR-GNDM^® technology with a muscle tropic AAV delivery system, has significant potential as a breakthrough treatment for FSHD.”